Biography
Major research interests include:
- clinical management of head and neck, lung, and skin cancers
- innovations in radiation therapy
- combinations of targeted therapy and immunotherapy with radiation
- virally driven cancers such as HPV, EBV, and Merkel cell polyomavirus
- radiation protectants
- patient-centered decision making
- tobacco cessation
- publication and research ethics
Education
| Institution | Degree | Dept or School | End Date |
|---|---|---|---|
| University of California, San Francisco | Certificate | Diversity, Equity, and Inclusion Champion Training | 9/2020 |
| University of California, San Francisco | M.A.S. | Clinical Research | 6/2016 |
| M.D. Anderson Cancer Center | Residency | Radiation Oncology | 6/2007 |
| University of Pennsylvania | M.D. | School of Medicine | 6/2002 |
Board Certifications
- American Board of Radiology
Clinical Expertise
Brachytherapy
Bronchioloalveolar Carcinoma (BAC)
Chemoradiation
CyberKnife irradiation for lung and skull base
Electron beam and orthovoltage irradiation
External-beam radiation therapy
Head & Neck Cancer
Hyperthemia
Intensity-modulated radiation therapy
Non-Small Cell Lung Cancer
Small-Cell Lung Cancer
Program Affiliations
- Thoracic Oncology Program
- Head and Neck Oncology Program
- Visible Tumor and High-Risk Skin Cancer Program
- Department of Radiation Oncology
Grants and Funding
- Oral microbiome and inflammatory status in antimicrobially-treated oral cancer patients | NIH | 2022-06-13 - 2027-05-31 | Role: Principal Investigator
Research Narrative
In lung cancer, Dr. Yom has conducted research quantifying the risks of pneumonitis and esophagitis when chemotherapy and radiation are given simultaneously. Her research findings were important in establishing the early use of intensity-modulated radiation therapy for lung cancer in combination with 4-dimensional CT-based planning. She has particular expertise in the delivery of chemoradiation therapy for advanced-stage lung cancer, and also the delivery of non-invasive stereotactic CyberKnife radiation for early-stage lung cancer. Her hope is that better understanding of radiation toxicities will permit higher treatment doses, increase the rate of cure and improve patient quality of life. She is strongly committed to research that will lead to more effective, less toxic, and more highly individualized therapy for patients.
Dr. Yom is an investigator on many research studies in head and neck and lung cancer at UCSF, including trials related to to image-guided radiation, head and neck patients' quality of life, and combinations of novel systemic agents with radiation therapy. She is especially interested in improved clinical and translational prognostic models in order to provide more effective and individualized therapy. It is hoped that the reduction of toxicities, both through technical and biologic means, will improve patients' quality of life and potentially enable physicians to deliver more intelligently targeted radiation and chemotherapy doses in search of a better chance of cure. She believes in multidisciplinary management and a unified, team-oriented approach to patient care
Research Interests
- Head and neck and lung cancers
- Advanced imaging and radiation planning
- Radiation in combination with chemotherapy and targeted agents
- Image-guided and adaptive radiation therapy
- Radiation sensitizers and protectors
- Outcomes and quality of life
Publications
- Mechanisms Underlying an Enhanced Navigation-Based Intervention to Improve Timely Adjuvant Therapy: A Secondary Analysis of the NDURE Randomized Clinical Trial.| |
PubMed
- Inconsistent definitions of local control for stereotactic body radiation therapy for early-stage lung cancer - A systematic review.| |
PubMed
- Driving progress in recurrent and metastatic head and neck cancer: the NRG Oncology perspective.| |
PubMed
- Integrative Oncology Approaches for Gastrointestinal Symptoms and Risk Reduction in Patients With Digestive Tract Cancers.| |
PubMed
- Reirradiation for recurrent head and neck squamous cell carcinoma: international expert consensus recommendations endorsed by the Reirradiation Collaborative Group, the European Society for Radiotherapy and Oncology Reirradiation Focus Group, and the Amer| |
PubMed
- Salvage of locoregionally recurrent head and neck cancer: an NRG oncology working group review.| |
PubMed
- The Role of the Microbiome and Gut Health in Patients With Digestive Tract Cancers.| |
PubMed
- Beyond stage and HPV status: the evolving landscape and future of multidisciplinary deintensification in human papillomavirus-related oropharyngeal cancer.| |
PubMed
- Emerging Treatments and Novel Modalities in Head and Neck Cancers.| |
PubMed
- Defining the Role of SABR in Head and Neck Cancer: Results from a Multi-institutional Delphi Consensus.| |
PubMed